CDC ORISE fellow position - December 2014

CDC has a fellowship opening to be filled as soon as possible.

They are looking for an applicant that has already graduated with either a BS or a MS in a chemistry/biology related science. A minimum GPA of 3.0 is required and mass spectrometry experience is highly preferred.

Georgia Tech graduates are highly respected in the Division of Laboratory Sciences.

If you would like to be considered for this position: please send resume to John Lee at ito7@cdc.gov.

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The positions are located in the Tobacco Exposure Biomarkers Laboratory, Emergency Response
and Air Toxicants Branch, Division of Laboratory Sciences (DLS), National Center for Environmental Health, CDC (Atlanta, Georgia). DLS is seeking multiple chemists (BS, MS and PhD) to work full-time on a regular shift supporting projects in the Tobacco Exposure Biomarkers Laboratory. The selected persons will be responsible for providing analytical support for the analysis of tobacco exposure biomarkers, including projects associated with FDA regulation of tobacco products.

The incumbents are expected to improve existing and develop new analytical methods to measure
tobacco exposure biomarkers using various sample preparation techniques and instrumentations,
including liquid-liquid extraction, solid-phase extraction, GC/MS/MS and LC/MS/MS. These positions will also involve performing routine sample analysis on GC/MS/MS or LC/MS/MS instrumentation, including analyzing samples, checking chromatograms, etc. In addition, these positions also require the selected persons to maintain instrument at highest sensitivity possible daily, update instrument service records and sample log at regular basis, trouble shoots the analytical method and instrument when there is a problem in the assay, and participate in data review and data compilation. The selected applicants will also have to interface with various laboratory staff and management to determine specific needs and to assist with implementation and maintenance. The selected applicants will have to obtain and maintain a CDC security clearance. Relocation allowances are not authorized for this position.

Primary job responsibilities will include:

1. Develop new analytical methods to measure tobacco exposure biomarkers using various sample
preparation techniques and instrumentations, including liquid-liquid extraction, solid-phase extraction,
GC/MS/MS and LC/MS/MS.
2. Perform routine sample preparation on automation systems, including check in samples, restock lab
supplies, maintain robotic systems, etc.
3. Perform routine sample analysis on GC/MS/MS or LC/MS/MS instrument, including analyzing
samples, checking chromatograms, etc.
4. Maintain and tune instrument at regular basis. Maintain instrument service records and sample log.
5. Trouble shoots the entire analytical method when there is a problem in the assay. Maintain highest
sensitivity possible daily for routine sample analysis.
6. Interface with various laboratory staff and management to determine specific needs and to assist with
implementation and maintenance. Provide technical guidance to junior scientists.
7. Participate in data review and analysis.
8. Adhere to CLIA Guidelines with regard to laboratory protocols and quality control. Assist in
maintaining various lab records and in survey sample management.

Requirements:

1. BS, MS or PhD in Chemistry or related science with a minimum GPA of 3.0.
2. Experienced in operating and maintaining analytical instrumentation: HPLC, UPLC, GC/MS/MS or
LC/MS/MS.
3. Knowledgeable in isotope dilution mass spectrometry.
4. Experienced in troubleshooting HPLC and tandem mass spectrometer.
5. Proficiency in the use of SAS, EXCEL, WORD, and PowerPoint software.
6. Excellent at being meticulous, detail-oriented, neat and organized.
7. Excellent at keeping records.
8. Excellent written and verbal skills. Good at team work.
Preferred Experience:
9. Experienced in developing analytical methods to measure biomarkers of exposure or effect in
biological samples.
10. Experienced in operating and maintaining automation robotic systems: Hamilton STAR, TECAN Freedom, Caliper Sciclone, etc.
11. Experienced with biological sample preparation techniques: solid phase extraction (SPE) and Liquid-liquid extraction (L-L).
12. Familiar with CLIA regulation, or other ISO, GLP guidelines.

If you would like to be considered for this position: please send resume to John Lee at ito7@cdc.gov.